Publications

Highly Sensitive Ratiometric Fluorescent Fiber Matrixes for Oxygen Sensing with Micrometer-Spatial Resolution (2024)
Grasso G., Onesto V., Forciniti S., D’Amone E., Colella F., Pierantoni L., Famà V., Gigli G., Reis R.L., Oliveira J.M., del Mercato L.L.
Bio-Design and Manufacturing (under publication).

Multilayer polyelectrolyte capsules for sensing and drug delivery: Fundamentals and applications (2024)
del Mercato L.L., Leporatti S., Ferraro M.M., Hanafy N.A., Rinaldi R., Parak W.J., Carregal-Romero S.
Chapter 57 in: W. J. Parak (ed.), Bio-Nano Interfaces: Perspectives, Properties, and Applications, Jenny Stanford Publishing, (1st ed.) Singapore (2024) https://doi.org/10.1201/9781003306498.

NIR ICG-Enhanced Fluorescence: A Quantitative Evaluation of Bowel Microperfusion and Its Relation to Central Perfusion in Colorectal Surgery (2023)
Depalma N., D’Ugo S., Manoochehri F., Libia A., Sergi W., Marchese T.R.L. , Forciniti S., del Mercato L.L., Piscitelli P., Garritano S., Castellana F., Zupo R., Spampinato M.G.
Cancers 2023, 15, 23, 5528 (DOI: https://doi.org/10.3390/cancers15235528) (ArXiv.org).

Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications (2023)
Grasso G., Colella F., Forciniti S., Onesto V., Iuele H., Siciliano A.C., Carnevali F., Chandra A., Gigli G., del Mercato L.L.
Nanoscale Advances 2023, 4311-4336 (DOI: 10.1039/D3NA00218G
) (ArXiv.org). Front cover.

pH-Sensing Hybrid Hydrogels for Non-Invasive Metabolism Monitoring in Tumor Spheroids (2023)
Rizzo R., Onesto V., 
Morello G., Iuele H., Scalera F., S Download naver photos. Forciniti, Gigli G., Polini A., Gervaso F., del Mercato L.L.
Materials Today Bio, 2023, 20, 100655 (DOI https://doi.org/10.1016/j.mtbio.2023.100655) (SSRN).

Quantifying heterogeneity to drug response in cancer-stroma kinetics (2023)
Alemanno F., Cavo M., Delle Cave D., Fachechi A., Rizzo R., D’Amone E., Gigli G., Lonardo E., Barra A., del Mercato L.L.

Proceedings of the National Academy of Sciences (PNAS), 2023, 120 (11) e2122352120.

Probing single cell fermentation fluxes and exchange networks via pH-sensing hybrid nanofibers (2023)
Onesto V., Forciniti S., Alemanno A., Krishnadev N., Chandra A., Prasad S., Azzariti A., Gigli G., Barra A., De Martino A., De Martino D., del Mercato L.L.
ACS Nano, 2023, 17, 4, 3313–3323 (DOI: 10.1021/acsnano.2c06114) (bioRxiv.org). Front Cover.

Preparation and Investigation of Thermally Annealed Zein-Propolis Electrospun Nanofibers for Biomedical Applications (2023)
Hochheim, S., Sampaio, N. M. F. M., da Cruz, A. F., del Mercato, L. L., D’Amone, E., da Silva, B. J. G., Saul, C. K., de Oliveira, C. C., Riegel-Vidotti, I.
Macromolecular Bioscience, 2023, 2200524 (DOI: 10.1021/acsnano.2c06114).  

A pH-Sensor Scaffold for Mapping Spatiotemporal Gradients in Three Dimensional In Vitro Tumour Models (2022)
Rizzo R., Onesto V., Forciniti S., Chandra A., Prasad S., Iuele H., Colella F., Gigli G., del Mercato L.L 외기러기. 
Biosensors and Bioelectronics, 2022, 15, 114401 (DOI: 10.1016/j.bios.2022.114401) (ArXiv.org).

Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors (2022)
Chandra A., Prasad S., Alemanno F., De Luca M., Rizzo R., Romano R., Gigli G., Bucci C., Barra A., del Mercato L.L. 
ACS Applied Materials & Interfaces, 2022, 14, 16, 18133–18149 (DOI: 10.1021/acsami.2c00389). Cover.

Co-loading of Doxorubicin and Iron Oxide Nanocubes in Polycaprolactone Fibers for Combining Magneto-Thermal and Chemotherapeutic Effects on Cancer Cells (2022)
Serio F., Silvestri N., Kumar Avugadda S., Nucci G., Nitte S., D’Amone E., Onesto V., Gigli G., del Mercato L.L., Pellegrino T.
Journal of Colloid And Interface Science, 2022, 607, 34-44 (DOI: 10.1016/j.jcis.2021.08.153) (ArXiv.org).

Electrospun polyvinyl-alcohol/gum arabic nanofibers: biomimetic platform for in vitro cell growth and cancer nanomedicine delivery (2021)
Serio F., Fraga da Cruz A., Chandra A., Nobile C., Rodrigues Rossi G., D’Amone E., Gigli G., del Mercato L.L., Camargo de Oliveira C.
International Journal of Biological Macromolecules, 2021, 188, 764-773 (DOI: 10.1016/j.ijbiomac.2021.08.069).

Highly sensitive fluorescent pH microsensor based on the ratiometric dye pyranine immobilized on silica microparticles (2021)
Chandra A., Prasad S., Iuele H., Colella F., Rizzo R., D’Amone E., Gigli G., del Mercato L.L.
Chemistry – A European Journal, 2021, 27, 53, 20, 13318-13324 (DOI: 10.1002/chem.202101568) (ArXiv.org). Front Cover Download Rebecca.

Cover Profile: Highly sensitive fluorescent pH microsensor based on the ratiometric dye pyranine immobilized on silica microparticles (2021)
Chandra A., Prasad S., Iuele H., Colella F., Rizzo R., D’Amone E., Gigli G., del Mercato L.L.
Chemistry – A European Journal, 2021, 27, 13279 (DOI: 10.1002/chem.202102674).

The revolutionary roads to study cell-cell interactions in 3D in vitro pancreatic cancer models (2021)
Delle Cave, D., Rizzo, R., Sáinz Jr B., Gigli, G., del Mercato, L.L., Lonardo, E.
Cancers, 2021, 13, 4, 930.

Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review future trends (2021)
Prasad S., Chandra A., Cavo M., Parasido E., Fricke S., Lee Y., D’Amone E., Gigli G., Albanese C., Rodriguez O., del Mercato L.L.
Nanotechnology, 2021, 32, 062001 (36pp) (ArXiv.org).

Beyond gold nanoparticles cytotoxicity: potential to impair metastasis hallmarks (2020)
Gonçalves J.P., Fraga da Cruz A., de Barros H.R., Borges B.S., de Medeiros L.C.A.S., Soares M.J.,  Padovan dos Santos M., Grassi M.T., Chandra A., del Mercato L.L., Rossi G.R., da Silva Trindade E., Riegel Vidotti I.C., de Oliveira C.C.
European Journal of Pharmaceutics and Biopharmaceutics,  2020, 157, 221-232. (ArXiv.org).

Electrospun nanofibers in cancer research: from engineering of in vitro 3D cancer models to therapy (2020)
Cavo M., Serio F., Kale N.R., D’Amone E., Gigli G., del Mercato L.L Download Sandol Cinema Theater.
Biomaterials Science, 2020, 8, 4887 – 4905. (ArXiv.org). Inside Front Cover.

Probing the pH microenvironment of mesenchymal stromal cell cultures on additive-manufactured scaffolds (2020)
Lorenzo Moldero, I., Chandra, A., Cavo, M., Mota, C., Kapsokalyvas, D., Gigli, G., Moroni, L., del Mercato, L.L.
Small, 2020, 16, 2002258. (ArXiv.org). Inside Front Cover

A synergic approach to enhance long-term culture and manipulation of MiaPaCa-2 pancreatic cancer spheroids (2020)
Cavo, M., Delle Cave, D., D’Amone, E., Gigli, G., Lonardo E., del Mercato, L.L.
Scientific Reports, 2020, 10, 10192. (ArXiv.org).

Fluorescent Nanoparticles for sensing (2020)
Chandra, A., Prasad, S., Gigli, G., del Mercato, L.L.
Frontiers of Nanoscience J. (ELSEVIER), 2020, 16, 117–149 한컴타자연습 2018. (ArXiv.org).

Gene expression studies using microgel embedded pancreatic cancer spheroids (2020)
Prasad, S., Chandra, A., Lonardo, E., Parasido, E., Albanese, C., del Mercato, L.L.
Cancer Res August 1 2020 (80) (16 Supplement) A1577; DOI: 10.1158/1538-7445.AM2020-1577.

Microgel-based in vitro tumoroid platform for real time assessment of drug sensitivity and resistance (2020)
Chandra, A., Prasad, S., Alemanno, F., Barra, A., Lonardo, E., Parasido, E., Albanese, C., del Mercato, L.L.
Cancer Res August 1 2020 (80) (16 Supplement) A2967; DOI: 10.1158/1538-7445.AM2020-2967.

Quantifying stroma-tumor cell interactions in three-dimensional cell culture systems (2020)
Cavo, M., Alemanno, F., Delle Cave, D., D’Amone, E., Barra, A., Lonardo, E., Parasido, E., Albanese, C., del Mercato, L.L.
Cancer Res June 1 2020 (80) (11 Supplement) A48; DOI: 10.1158/1538-7445.CAMODELS2020-A48.

Mixing enhancement induced by viscoelastic micromotors in microfluidic platform (2019)
Zizzari, A., Cesaria, M., Bianco, M. del Mercato, L.L., Carraro, M., Bonchio, M., Rella, R., Arima V.
Chemical Engineering Journal, Volume 391, 1 July 2020, 123572. (ArXiv.org).

Towards the development of human immune-system-on-a-chip platforms (2019)
Polini, A., del Mercato, L.L., Barra, A., Zhang, Y.S., Calabi, F., Gigli, G.
Drug Discovery Today, 2019, 24 (2), 517-525. (ArXiv.org) 책 pdf.

Highly Sensitive Membrane-Based Pressure Sensors (MePS) for Real-Time Monitoring of Catalytic Reactions (2018)
Zizzari, A., Bianco, M., del Mercato, L.L., Sorarù, A., Carraro, M., Pellegrino, P., Perrone, E., Monteduro, A.G., Bonchio, M., Rinaldi, R., Viola, I., Arima, V.
Analytical Chemistry, 2018, 90 (12), 7659-7665.

Emerging technologies for cancer research: Towards personalized medicine with microfluidic platforms and 3D tumor models (2018)
Turetta, M., Del Ben, F., Brisotto, G., Biscontin, E., Bulfoni, M., Cesselli, D., Colombatti, A., Scoles, G., Gigli, G., del Mercato, L.L.
Current Medicinal Chemistry, 2018, 25 (35), 4616-4637. (ArXiv.org).

Self-powered catalytic microfluidic platforms for fluid delivery (2017)
Zizzari, A., Bianco, M., del Mercato, L.L., Carraro, M., Bonchio, M., Frigione, M., Montagna, F., Gigli, G., Viola, I., Arima, V.
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2017, 532, 257-262.

Multilayered Magnetic Nanobeads for the Delivery of Peptides Molecules Triggered by Intracellular Proteases (2017)
Quarta, A., Rodio, M., Cassani, M., Gigli, G., Pellegrino, T., del Mercato, L.L.
ACS Applied Materials and Interfaces, 2017, 9 (40), 35095-35104.

Anticancer effects of novel resveratrol analogues on human ovarian cancer cells (2017)
Vergara, D., De Domenico, S., Tinelli, A., Stanca, E., del Mercato, L.L., Giudetti, A.M., Simeone, P., Guazzelli, N., Lessi, M., Manzini, C., Santino, A., Bellina, F., Maffia, M.
Molecular BioSystems, 2017, 13 (6), 1131-1141.

Design and characterization of microcapsules-integrated collagen matrixes as multifunctional three-dimensional scaffolds for soft tissue engineering (2016)
del Mercato, L.L., Passione, L.G., Izzo, D., Rinaldi, R., Sannino, A., Gervaso, F.
Journal of the Mechanical Behavior of Biomedical Materials, 2016, 62, 209-221.

Biocompatible multilayer capsules engineered with a graphene oxide derivative: Synthesis, characterization and cellular uptake (2016)
del Mercato, L.L., Guerra, F., Lazzari, G., Nobile, C., Bucci, C., Rinaldi, R.
Nanoscale, 2016, 8 (14), 7501-7512.

Ratiometric Organic Fibers for Localized and Reversible Ion Sensing with Micrometer-Scale Spatial Resolution (2015)
del Mercato, L.L., Moffa, M., Rinaldi, R., Pisignano, D.
Small, 2015, 11 (48), 6417-6424.

Nanofibers: Ratiometric Organic Fibers for Localized and Reversible Ion Sensing with Micrometer-Scale Spatial Resolution (Small 48/2015) (2015)
del Mercato, L.L., Moffa, M., Rinaldi, R., Pisignano, D 잔나비 2집.
Small (Weinheim an der Bergstrasse, Germany), 2015, 11 (48), 6416. Frontispiece.

Cytoskeletal Alterations and Biomechanical Properties of parkin-Mutant Human Primary Fibroblasts (2015)
Vergara, D., Ferraro, M.M., Cascione, F., del Mercato, L.L., Leporatti, S., Ferretta, A., Tanzarella, P., Pacelli, C., Santino, A., Maffia, M., Cocco, T., Rinaldi, R., Gaballo, A.
Cell Biochemistry and Biophysics, 2015, 71 (3), 1395-1404.

Advances in Use of Capsule-Based Fluorescent Sensors for Measuring Acidification of Endocytic Compartments in Cells with Altered Expression of V-ATPase Subunit V1G1 (2015)
De Luca, M., Ferraro, M.M., Hartmann, R., Rivera-Gil, P., Klingl, A., Nazarenus, M., Ramirez, A., Parak, W.J., Bucci, C., Rinaldi, R., del Mercato, L.L.
ACS Applied Materials and Interfaces, 2015, 7 (27), 15052-15060.

Catalytic oxygen production mediated by smart capsules to modulate elastic turbulence under a laminar flow regime (2014)
Zizzari, A., Bianco, M., Miglietta, R., del Mercato, L.L., Carraro, M., Sorarù, A., Bonchio, M., Gigli, G., Rinaldi, R., Viola, I., Arima, V.
Lab on a Chip, 2014, 14 (22), 4391-4397.

Catalytic self-propulsion of supramolecular capsules powered by polyoxometalate cargos (2014)
del Mercato, L.L., Carraro, M., Zizzari, A., Bianco, M., Miglietta, R., Arima, V., Viola, I., Nobile, C., Sorarù, A., Vilona, D., Gigli, G., Bonchio, M., Rinaldi, R.
Chemistry – A European Journal, 2014, 20 (35), 10910-10914.

Biological applications of LbL multilayer capsules: From drug delivery to sensing (2014)
del Mercato, L.L., Ferraro, M.M., Baldassarre, F., Mancarella, S., Greco, V., Rinaldi, R., Leporatti, S.
Advances in Colloid and Interface Science, 2014, 207 (1), 139-154.

Cytoskeletal alterations of parkin-mutant human primary fibroblasts (2014)
Vergara, D., Ferraro, M.M., Ferretta A., Cascione, F., del Mercato, L.L., Rinaldi, R., Maffia, M., Leporatti, S., Santino, A., Cocco, T., Gaballo, A.
Journal of Biotechnology, 2014, 185, S27-S28.

Multiplexed sensing of ions with barcoded polyelectrolyte capsules (2011)
del Mercato, L.L., Abbasi, A.Z., Ochs, M., Parak, W.J.
ACS Nano, 2011, 5 (12), 9668-9674.

Synthesis and evaluation of gold nanoparticle-modified polyelectrolyte capsules under microwave irradiation for remotely controlled release for cargo (2011)
del Mercato, L.L., Gonzalez, E., Abbasi, A.Z., Parak, W.J., Puntes, V.
Journal of Materials Chemistry, 2011, 21 (31), 11468-11471.

Magnetic capsules for NMR imaging: Effect of magnetic nanoparticles spatial distribution and aggregation (2011)
Abbasi, A.Z., Gutiérrez, L., del Mercato, L.L., Herranz, F., Chubykalo-Fesenko, O., Veintemillas-Verdaguer, S., Parak, W.J., Morales, M.P., González, J.M., Hernando, A., De La Presa, P Download minecraft story mode.
Journal of Physical Chemistry C, 2011, 115 (14), 6257-6264.

Synthesis and characterization of ratiometric ion-sensitive polyelectrolyte capsules (2011)
del Mercato, L.L., Abbasi, A.Z., Parak, W.J.
Small, 2011, 7 (3), 351-363.

De novo design of supercharged, unfolded protein polymers, and their assembly into supramolecular aggregatesa (2011)
Kolbe, A., del Mercato, L.L., Abbasi, A.Z., Gil, P.R., Gorzini, S.J., Huibers, W.H.C., Poolman, B., Parak, W.J., Herrmann, A.
Macromolecular Rapid Communications, 2011, 32 (2), 186-190.

Nanopharmacy: Inorganic nanoscale devices as vectors and active compounds (2010)
Rivera-Gil, P., Hühn, D., del Mercato, L.L., Sasse, D., Parak, W.J.
Pharmacological Research, 2010, 62 (2), 115-125.

LbL multilayer capsules: Recent progress and future outlook for their use in life sciences (2010)
del Mercato, L.L., Rivera-Gil, P., Abbasi, A.Z., Ochs, M., Ganas, C., Zins, I., Sönnichsen, C., Parak, W.J.
Nanoscale, 2010, 2 (4), 458-467. Inside front cover

Amyloid fibrils: from nature to nanotechnology (2010)
Sabella, S., Pompa, P.P., Sorce, B., del Mercato L.L., Rinaldi, R.
Functional Amyloid Aggregation, Research Signpost 37/661 (2), Fort P.O. Trivandrum-695 023 Kerala, India Functional Amyloid Aggregation, 2010: 157-189 ISBN: 978-81-308-0425-5 Editors: Stefania Rigacci and Monica Bucciantini.

One example on how colloidal nano- and microparticles could contribute to medicine (2009)
Peteiro-Cartelle, J., Rodríguez-Pedreira, M., Zhang, F., Gil, P.R., del Mercato, L.L., Parak, W.J.
Nanomedicine, 2009, 4 (8), 967-979.

Relaxation times of colloidal iron platinum in polymer matrixes (2009)
Morales, M.P., Bédard, M.F., Roca, A.G., De La Presa, P., Hernando, A., Zhang, F., Zanella, M., Zahoor, A.A., Sukhorukov, G.B., del Mercato, L.L., Parak, W.J.
Journal of Materials Chemistry, 2009, 19 (35), 6381-6386.

Exploring local flexibility/rigidity in psychrophilic and mesophilic carbonic anhydrases (2009)
Chiuri, R., Maiorano, G., Rizzello, A., del Mercato, L.L., Cingolani, R., Rinaldi, R., Maffia, M., Pompa, P.P.
Biophysical Journal, 2009, 96 (4), 1586-1596.

Nanoparticle-modified polyelectrolyte capsules (2008)
Rivera-Gil, P., del Mercato, L.L., del Pino, P., Muñoz-Javier, A., Parak, W.J 한글 오피스 무료.
Nano Today, 2008, 3 (3-4), 12-21.

Interconnection of specific nano-objects by electron beam lithography – A controllable method (2008)
Della Torre, A., Pompa, P.P., del Mercato, L.L., Chiuri, R., Krahne, R., Maruccio, G., Carbone, L., Manna, L., Cingolani, R., Rinaldi, R., Shankar, S.S., Sastry, M.
Materials Science and Engineering C, 2008, 28 (2), 299-302.

Amyloid-like fibrils in elastin-related polypeptides: Structural characterization and elastic properties (2008)
del Mercato, L.L., Maruccio, G., Pompa, P.P., Bochicchio, B., Tamburro, A.M., Cingolani, R., Rinaldi, R.
Biomacromolecules, 2008, 9 (3), 796-803.

Charge transport and intrinsic fluorescence in amyloid-like fibrils (2007)
del Mercato, L.L., Pompa, P.P., Maruccio, G., Della Torre, A., Sabella, S., Tamburro, A.M., Cingolani, R., Rinaldi, R.
Proceedings of the National Academy of Sciences (PNAS), 2007, 104 (46), 18019-18024.

Fluorescence enhancement in colloidal semiconductor nanocrystals by metallic nanopatterns (2007)
Pompa, P.P., Martiradonna, L., Torre, A.D., Carbone, L., del Mercato, L.L., Manna, L., De Vittorio, M., Calabi, F., Cingolani, R., Rinaldi, R.
Sensors and Actuators, B: Chemical, 2007, 126 (1), 187-192.

Interconnecting single nano-objects on surfaces for transport experiments (2006)
Della Torre, A., Pompa, P.P., del Mercato, L.L., Cingolani, R., Rinaldi, R., Shiv Shankar, S., Sastry, M.
Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures, 2006, 24 (6), 2765-2768.

Charge transport in disordered films of non-redox proteins (2006)
Pompa, P.P., Della Torre, A., del Mercato, L.L., Chiuri, R., Bramanti, A., Calabi, F., Maruccio, G., Cingolani, R., Rinaldi, R.
Journal of Chemical Physics, 2006, 125 (2), 021103, .

Fluorescence resonance energy transfer induced by conjugation of metalloproteins to nanoparticles (2006)
Pompa, P.P., Chiuri, R., Manna, L., Pellegrino, T., del Mercato, L.L., Parak, W.J., Calabi, F., Cingolani, R., Rinaldi, R.
Chemical Physics Letters, 2006, 417 (4-6), 351-357.

Effects of high external electric fields on protein conformation (2005)
Pompa, P.P., Bramanti, A., Maruccio, G., del Mercato, L.L., Chiuri, R., Cingolani, R., Rinaldi, R.
Proceedings of SPIE – The International Society for Optical Engineering, 2005, 5838, 27, 171-181 Hangul 2014 vp for mac.

Ageing of solid-state protein films: Behavior of azurin at ambient conditions (2005)
Pompa, P.P., Bramanti, A., Maruccio, G., del Mercato, L.L., Cingolani, R., Rinaldi, R.
Chemical Physics Letters, 2005, 404 (1-3), 59-62.